Cellular reprogramming through mitogen-activated protein kinases
نویسندگان
چکیده
منابع مشابه
Cellular reprogramming through mitogen-activated protein kinases
Mitogen-activated protein kinase (MAPK) cascades are conserved eukaryote signaling modules where MAPKs, as the final kinases in the cascade, phosphorylate protein substrates to regulate cellular processes. While some progress in the identification of MAPK substrates has been made in plants, the knowledge on the spectrum of substrates and their mechanistic action is still fragmentary. In this fo...
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Mitogen-Activated Protein Kinase Cascades: Terminology and Properties The best-characterized subfamilies of the mitogen-activated protein kinase (MAPK) superfamily are the extracellularly responsive kinases (ERKs) and the two “stress-responsive” MAPK subfamilies, namely, the c-Jun N-terminal kinases (JNKs) and the p38-MAPKs. As yet, no single nomenclature has been determined, and the synonyms c...
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PURPOSE Mitogen-activated protein kinases (MAPKs), consisting of three major enzymes-extracellular signal-regulated kinase (ERK), p38, and c-jun N-terminal kinase (JNK)-couple cell-surface receptors to critical regulatory targets and gene transcription. We hypothesized that MAPKs are differentially expressed and have distinct functions after retinal ischemia. METHODS Rats were subjected to re...
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Mitogen-activated protein kinases (MAPKs) play critical regulatory roles in the production of the pro-inflammatory cytokines and downstream signaling events which lead to inflammation. Inflammation is a primarily localized and protective response of host against microbial infection. Controlled inflammation is beneficial and necessary for host defense while uncontrolled inflammatory response res...
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ژورنال
عنوان ژورنال: Frontiers in Plant Science
سال: 2015
ISSN: 1664-462X
DOI: 10.3389/fpls.2015.00940